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Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex

The entorhinal cortex (EC) plays a central role in episodic memory and is among the earliest sites of neurodegeneration and neurofibrillary tangle formation in Alzheimer's disease. Given its importance in memory and dementia, the ability to selectively modulate gene expression or neuronal funct...

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Bibliographic Details
Published in:Brain Struct Funct
Main Authors: Yetman, Michael J., Lillehaug, Sveinung, Bjaalie, Jan G., Leergaard, Trygve B., Jankowsky, Joanna L.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605847/
https://ncbi.nlm.nih.gov/pubmed/25869275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-015-1040-9
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