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A Genome-Wide Screen for Machinery Involved in Downregulation of MHC Class I by HIV-1 Nef
The HIV-1-encoded protein, Nef, plays a key role in the development of AIDS. One of Nef’s functions is to keep MHC class I off the surface of infected cells, a process that requires the host proteins clathrin and AP-1. To identify other proteins involved in this pathway, we carried out a genome-wide...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4605695/ https://ncbi.nlm.nih.gov/pubmed/26466362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140404 |
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