HIV-1 Nef-induced Down-Regulation of MHC Class I Requires AP-1 and Clathrin but Not PACS-1 and Is Impeded by AP-2

Major histocompatibility complex class I is down-regulated from the surface of human immunodeficiency virus (HIV)-1-infected cells by Nef, a virally encoded protein that is thought to reroute MHC-I to the trans-Golgi network (TGN) in a phosphofurin acidic cluster sorting protein (PACS) 1, adaptor pr...

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Detalhes bibliográficos
Main Authors: Lubben, Nienke B., Sahlender, Daniela A., Motley, Alison M., Lehner, Paul J., Benaroch, Philippe, Robinson, Margaret S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951775/
https://ncbi.nlm.nih.gov/pubmed/17581864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-03-0218
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