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Clathrin-mediated endocytosis in AP-2–depleted cells

We have used RNA interference to knock down the AP-2 μ2 subunit and clathrin heavy chain to undetectable levels in HeLaM cells. Clathrin-coated pits associated with the plasma membrane were still present in the AP-2–depleted cells, but they were 12-fold less abundant than in control cells. No clathr...

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Autori principali: Motley, Alison, Bright, Nicholas A., Seaman, Matthew N.J., Robinson, Margaret S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172830/
https://ncbi.nlm.nih.gov/pubmed/12952941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200305145
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