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Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2
The critical initiation phase of clathrin-mediated endocytosis (CME) determines where and when endocytosis occurs. Heterotetrameric adaptor protein 2 (AP2) complexes, which initiate clathrin-coated pit (CCP) assembly, are activated by conformational changes in response to phosphatidylinositol-4,5-bi...
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| Veröffentlicht in: | J Cell Biol |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5223608/ https://ncbi.nlm.nih.gov/pubmed/28003333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201608071 |
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