Clathrin-mediated endocytosis in AP-2–depleted cells

We have used RNA interference to knock down the AP-2 μ2 subunit and clathrin heavy chain to undetectable levels in HeLaM cells. Clathrin-coated pits associated with the plasma membrane were still present in the AP-2–depleted cells, but they were 12-fold less abundant than in control cells. No clathr...

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Huvudupphovsmän: Motley, Alison, Bright, Nicholas A., Seaman, Matthew N.J., Robinson, Margaret S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2003
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172830/
https://ncbi.nlm.nih.gov/pubmed/12952941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200305145
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