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High PHLPP expression is associated with better prognosis in patients with resected lung adenocarcinoma
BACKGROUND: PH domain Leucine-rich-repeats protein phosphatase (PHLPP) is a novel family of Ser/Thr protein dephosphatases that play a critical role in maintaining the balance in cell signaling. PHLPP negatively regulates PI3K/Akt and RAF/RAS/′ signaling activation, which is crucial in development,...
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| Publicado no: | BMC Cancer |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4604720/ https://ncbi.nlm.nih.gov/pubmed/26463718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1711-1 |
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