Investigating Diagnostic Problems of CIN 1 and 2 Associated with High-Risk HPV by Combining the Novel Molecular Biomarker PanHPV E4 with P16(ink4a)

Grading cervical intraepithelial neoplasia (CIN) determines clinical management of women after abnormal cytology with potential for over-diagnosis and overtreatment. We studied a novel biomarker of HPV life-cycle completion (panHPVE4), in combination with the MCM cell-cycle marker and the p16(INK4a)...

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Pubblicato in:Am J Surg Pathol
Autori principali: van Baars, Romy, Griffin, Heather, Wu, Zhonglin, Soneji, Yasmina Jay, van de Sandt, Miekel, Arora, Rupali, van der Marel, Jacolien, ter Harmsel, Bram, Jach, Robert, Okon, Krzysztof, Huras, Hubert, Jenkins, David, Quint, Wim, Doorbar, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604656/
https://ncbi.nlm.nih.gov/pubmed/26379150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000498
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