Investigating Diagnostic Problems of CIN 1 and 2 Associated with High-Risk HPV by Combining the Novel Molecular Biomarker PanHPV E4 with P16(ink4a)

Grading cervical intraepithelial neoplasia (CIN) determines clinical management of women after abnormal cytology with potential for over-diagnosis and overtreatment. We studied a novel biomarker of HPV life-cycle completion (panHPVE4), in combination with the MCM cell-cycle marker and the p16(INK4a)...

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Publicado no:Am J Surg Pathol
Main Authors: van Baars, Romy, Griffin, Heather, Wu, Zhonglin, Soneji, Yasmina Jay, van de Sandt, Miekel, Arora, Rupali, van der Marel, Jacolien, ter Harmsel, Bram, Jach, Robert, Okon, Krzysztof, Huras, Hubert, Jenkins, David, Quint, Wim, Doorbar, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604656/
https://ncbi.nlm.nih.gov/pubmed/26379150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000498
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