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Molecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis

Colorectal cancer (CRC) is the third leading cause of death in both men and women in North America. Despite chemotherapeutic efforts, CRC is associated with a high degree of morbidity and mortality. Thus, to develop effective treatment strategies for CRC, one needs knowledge of the pathogenesis of c...

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Bibliografiske detaljer
Udgivet i:Life Sci
Main Authors: Narayan, Satya, Sharma, Ritika
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604609/
https://ncbi.nlm.nih.gov/pubmed/26334567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2015.08.019
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