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Mechanism of Adenomatous Polyposis Coli (APC)-mediated Blockage of Longpatch Base Excision Repair

Recently, we found an interaction between adenomatous polyposis coli (APC) and DNA polymerase β (pol-β) and showed that APC blocks strand-displacement synthesis of long-patch base excision repair (LP-BER) however, the mechanism is not clear. Using an in vivo LP-BER assay system, we now show that the...

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書誌詳細
主要な著者: Jaiswal, Aruna S., Balusu, Ramesh, Armas, Melissa L., Kundu, Chanakya N., Narayan, Satya
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528549/
https://ncbi.nlm.nih.gov/pubmed/17176113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0607958
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