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Molecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis

Colorectal cancer (CRC) is the third leading cause of death in both men and women in North America. Despite chemotherapeutic efforts, CRC is associated with a high degree of morbidity and mortality. Thus, to develop effective treatment strategies for CRC, one needs knowledge of the pathogenesis of c...

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Detalhes bibliográficos
Publicado no:Life Sci
Main Authors: Narayan, Satya, Sharma, Ritika
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604609/
https://ncbi.nlm.nih.gov/pubmed/26334567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2015.08.019
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