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Splicing promotes the nuclear export of β-globin mRNA by overcoming nuclear retention elements

Most current models of mRNA nuclear export in vertebrate cells assume that an mRNA must have specialized signals in order to be exported from the nucleus. Under such a scenario, mRNAs that lack these specialized signals would be shunted into a default pathway where they are retained in the nucleus a...

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Pubblicato in:RNA
Autori principali: Akef, Abdalla, Lee, Eliza S., Palazzo, Alexander F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604431/
https://ncbi.nlm.nih.gov/pubmed/26362019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.051987.115
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