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The Signal Sequence Coding Region Promotes Nuclear Export of mRNA

In eukaryotic cells, most mRNAs are exported from the nucleus by the transcription export (TREX) complex, which is loaded onto mRNAs after their splicing and capping. We have studied in mammalian cells the nuclear export of mRNAs that code for secretory proteins, which are targeted to the endoplasmi...

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Detalhes bibliográficos
Main Authors: Palazzo, Alexander F, Springer, Michael, Shibata, Yoko, Lee, Chung-Sheng, Dias, Anusha P, Rapoport, Tom A
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2100149/
https://ncbi.nlm.nih.gov/pubmed/18052610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050322
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