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The Signal Sequence Coding Region Promotes Nuclear Export of mRNA

In eukaryotic cells, most mRNAs are exported from the nucleus by the transcription export (TREX) complex, which is loaded onto mRNAs after their splicing and capping. We have studied in mammalian cells the nuclear export of mRNAs that code for secretory proteins, which are targeted to the endoplasmi...

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Detalles Bibliográficos
Main Authors: Palazzo, Alexander F, Springer, Michael, Shibata, Yoko, Lee, Chung-Sheng, Dias, Anusha P, Rapoport, Tom A
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2100149/
https://ncbi.nlm.nih.gov/pubmed/18052610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050322
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