The Signal Sequence Coding Region Promotes Nuclear Export of mRNA

In eukaryotic cells, most mRNAs are exported from the nucleus by the transcription export (TREX) complex, which is loaded onto mRNAs after their splicing and capping. We have studied in mammalian cells the nuclear export of mRNAs that code for secretory proteins, which are targeted to the endoplasmi...

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Dettagli Bibliografici
Autori principali: Palazzo, Alexander F, Springer, Michael, Shibata, Yoko, Lee, Chung-Sheng, Dias, Anusha P, Rapoport, Tom A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2100149/
https://ncbi.nlm.nih.gov/pubmed/18052610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050322
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