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Splicing promotes the nuclear export of β-globin mRNA by overcoming nuclear retention elements

Most current models of mRNA nuclear export in vertebrate cells assume that an mRNA must have specialized signals in order to be exported from the nucleus. Under such a scenario, mRNAs that lack these specialized signals would be shunted into a default pathway where they are retained in the nucleus a...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Akef, Abdalla, Lee, Eliza S., Palazzo, Alexander F.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604431/
https://ncbi.nlm.nih.gov/pubmed/26362019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.051987.115
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