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Functions of a GyrBA Fusion Protein and Its Interaction with QnrB and Quinolones

In order to study the interactions between Escherichia coli DNA gyrase and the gyrase interacting protein QnrB in vivo, we constructed a gyrB-gyrA fusion and validated its ability to correct the temperature-sensitive growth of gyrA and gyrB mutants. Like wild-type gyrA, the gyrB-gyrA fusion compleme...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Chen, Chunhui, Villet, Regis, Jacoby, George A., Hooper, David C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604398/
https://ncbi.nlm.nih.gov/pubmed/26324265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01845-15
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