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Functions of a GyrBA Fusion Protein and Its Interaction with QnrB and Quinolones

In order to study the interactions between Escherichia coli DNA gyrase and the gyrase interacting protein QnrB in vivo, we constructed a gyrB-gyrA fusion and validated its ability to correct the temperature-sensitive growth of gyrA and gyrB mutants. Like wild-type gyrA, the gyrB-gyrA fusion compleme...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Chen, Chunhui, Villet, Regis, Jacoby, George A., Hooper, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604398/
https://ncbi.nlm.nih.gov/pubmed/26324265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01845-15
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