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Functions of a GyrBA Fusion Protein and Its Interaction with QnrB and Quinolones

In order to study the interactions between Escherichia coli DNA gyrase and the gyrase interacting protein QnrB in vivo, we constructed a gyrB-gyrA fusion and validated its ability to correct the temperature-sensitive growth of gyrA and gyrB mutants. Like wild-type gyrA, the gyrB-gyrA fusion compleme...

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發表在:Antimicrob Agents Chemother
Main Authors: Chen, Chunhui, Villet, Regis, Jacoby, George A., Hooper, David C.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604398/
https://ncbi.nlm.nih.gov/pubmed/26324265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01845-15
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