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Analytical and Functional Determination of Polymyxin B Protein Binding in Serum

To enhance our understanding of the pharmacological properties of polymyxin B, serum protein binding for polymyxin B1, B2, and B3 and for isoleucine-polymyxin B1 was evaluated. Using equilibrium dialysis and ultrafiltration, comparable protein binding was found in all 4 components of polymyxin B (92...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Abodakpi, Henrietta, Gohlke, Jie, Chang, Kai-Tai, Chow, Diana S.-L., Tam, Vincent H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604353/
https://ncbi.nlm.nih.gov/pubmed/26324262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01815-15
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