Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice

AIM: Cardiac inflammation is important in the pathogenesis of heart failure. However, the consequence of systemic inflammation on concomitant established heart failure, and in particular diastolic heart failure, is less explored. Here we investigated the impact of systemic inflammation, caused by su...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Dhondup, Yangchen, Sjaastad, Ivar, Scott, Helge, Sandanger, Øystein, Zhang, Lili, Haugstad, Solveig Bjærum, Aronsen, Jan Magnus, Ranheim, Trine, Holmen, Sigve Dhondup, Alfsnes, Katrine, Ahmed, Muhammad Shakil, Attramadal, Håvard, Gullestad, Lars, Aukrust, Pål, Christensen, Geir, Yndestad, Arne, Vinge, Leif Erik
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604200/
https://ncbi.nlm.nih.gov/pubmed/26461521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139715
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