Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice

Aim. Inflammation is important in heart failure (HF). The role of the immune receptor toll-like receptor 9 (TLR9) in HF is not understood and not investigated in diastolic HF. We investigated the role of TLR9 in a murine diastolic HF model caused by cardiomyocyte SERCA2a excision. Methods and Result...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Dhondup, Yangchen, Sjaastad, Ivar, Sandanger, Øystein, Aronsen, Jan Magnus, Ahmed, Muhammad Shakil, Attramadal, Håvard, Finsen, Alexandra Vanessa, Zhang, Lili, Ranheim, Trine, Alfsnes, Katrine, Aukrust, Pål, Christensen, Geir, Yndestad, Arne, Vinge, Leif Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405589/
https://ncbi.nlm.nih.gov/pubmed/28490840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9450439
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