Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice

AIM: Cardiac inflammation is important in the pathogenesis of heart failure. However, the consequence of systemic inflammation on concomitant established heart failure, and in particular diastolic heart failure, is less explored. Here we investigated the impact of systemic inflammation, caused by su...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Dhondup, Yangchen, Sjaastad, Ivar, Scott, Helge, Sandanger, Øystein, Zhang, Lili, Haugstad, Solveig Bjærum, Aronsen, Jan Magnus, Ranheim, Trine, Holmen, Sigve Dhondup, Alfsnes, Katrine, Ahmed, Muhammad Shakil, Attramadal, Håvard, Gullestad, Lars, Aukrust, Pål, Christensen, Geir, Yndestad, Arne, Vinge, Leif Erik
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604200/
https://ncbi.nlm.nih.gov/pubmed/26461521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139715
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