Effect of Readthrough Treatment in Fibroblasts of Patients Affected by Lysosomal Diseases Caused by Premature Termination Codons

Aminoglycoside antibiotics, such as gentamicin, may induce premature termination codon (PTC) readthrough and elude the nonsense-mediated mRNA decay mechanism. Because PTCs are frequently involved in lysosomal diseases, readthrough compounds may be useful as potential therapeutic agents. The aim of o...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Neurotherapeutics
Huvudupphovsmän: Matalonga, Leslie, Arias, Ángela, Tort, Frederic, Ferrer-Cortés, Xènia, Garcia-Villoria, Judit, Coll, Maria Josep, Gort, Laura, Ribes, Antonia
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer US 2015
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604176/
https://ncbi.nlm.nih.gov/pubmed/26169295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-015-0368-4
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk