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The interaction of Gα(13) with integrin β(1) mediates cell migration by dynamic regulation of RhoA

Heterotrimeric G protein Gα(13) is known to transmit G protein–coupled receptor (GPCR) signals leading to activation of RhoA and plays a role in cell migration. The mechanism underlying the role of Gα(13) in cell migration, however, remains unclear. Recently we found that Gα(13) interacts with the c...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Shen, Bo, Estevez, Brian, Xu, Zheng, Kreutz, Barry, Karginov, Andrei, Bai, Yanyan, Qian, Feng, Norifumi, Urao, Mosher, Deane, Du, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603935/
https://ncbi.nlm.nih.gov/pubmed/26310447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-05-0274
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