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Comprehensive prediction of drug-protein interactions and side effects for the human proteome
Identifying unexpected drug-protein interactions is crucial for drug repurposing. We develop a comprehensive proteome scale approach that predicts human protein targets and side effects of drugs. For drug-protein interaction prediction, FINDSITE(comb), whose average precision is ~30% and recall ~27%...
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| Publicat a: | Sci Rep |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4603786/ https://ncbi.nlm.nih.gov/pubmed/26057345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11090 |
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