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Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism
Flux balance analysis is the only modelling approach that is capable of producing genome-wide predictions of gene essentiality that may aid to unveil metabolic liabilities in cancer. Nevertheless, a systemic validation of gene essentiality predictions by flux balance analysis is currently missing. H...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4603759/ https://ncbi.nlm.nih.gov/pubmed/26040780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10738 |
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