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Structural basis for profilin-mediated actin nucleotide exchange

Actin is a ubiquitous eukaryotic protein that is responsible for cellular scaffolding, motility and division. The ability of actin to form a helical filament is the driving force behind these cellular activities. Formation of a filament is dependent the successful exchange of actin’s ADP for ATP. Ma...

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Détails bibliographiques
Publié dans:J Mol Biol
Auteurs principaux: Porta, Jason C., Borgstahl, Gloria E.O.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603570/
https://ncbi.nlm.nih.gov/pubmed/22366544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.02.012
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