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Structural basis for profilin-mediated actin nucleotide exchange

Actin is a ubiquitous eukaryotic protein that is responsible for cellular scaffolding, motility and division. The ability of actin to form a helical filament is the driving force behind these cellular activities. Formation of a filament is dependent the successful exchange of actin’s ADP for ATP. Ma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Mol Biol
Hauptverfasser: Porta, Jason C., Borgstahl, Gloria E.O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603570/
https://ncbi.nlm.nih.gov/pubmed/22366544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.02.012
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