Extended O-GlcNAc on HLA class-I-bound peptides

We report unexpected mass spectrometric observations of glycosylated human leukocyte antigen (HLA) class I-bound peptides. Complemented by molecular modeling, in vitro enzymatic assays, and oxonium ion patterns, we propose that the observed O-linked glycans carrying up to five monosaccharides are ex...

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發表在:J Am Chem Soc
Main Authors: Marino, Fabio, Bern, Marshall, Mommen, Geert P.M., Leney, Aneika C., van Gaans-van den Brink, Jacqueline A.M., Bonvin, Alexandre M.J.J., Becker, Christopher, van Els, Cécile A.C.M., Heck, Albert J. R.
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603548/
https://ncbi.nlm.nih.gov/pubmed/26280087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b06586
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