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Non-germline genetically engineered mouse models for translational cancer research

Genetically engineered mouse models (GEMMs) of cancer have affected virtually all areas of cancer research. However, the accelerated discovery of new cancer genes emerging from large-scale cancer genomics and new chemical entities pouring from the drug discovery pipeline have strained the capacity o...

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Bibliografische gegevens
Gepubliceerd in:Nat Rev Cancer
Hoofdauteurs: Heyer, Joerg, Kwong, Lawrence N., Lowe, Scott W., Chin, Lynda
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602412/
https://ncbi.nlm.nih.gov/pubmed/20574449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2877
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