The relationship between infliximab concentrations, antibodies to infliximab and disease activity in Crohn's disease

OBJECTIVE: Although low infliximab trough concentrations and antibodies to infliximab (ATI) are associated with poor outcomes in patients with Crohn's disease (CD), the clinical relevance of ATI in patients with adequate infliximab concentrations is uncertain. We evaluated this question using a...

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Pubblicato in:Gut
Autori principali: Vande Casteele, Niels, Khanna, Reena, Levesque, Barrett G, Stitt, Larry, Zou, G Y, Singh, Sharat, Lockton, Steve, Hauenstein, Scott, Ohrmund, Linda, Greenberg, Gordon R, Rutgeerts, Paul J, Gils, Ann, Sandborn, William J, Vermeire, Séverine, Feagan, Brian G
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2015
Soggetti:
Inflammatory Bowel Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602247/
https://ncbi.nlm.nih.gov/pubmed/25336114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307883
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