The relationship between infliximab concentrations, antibodies to infliximab and disease activity in Crohn's disease

OBJECTIVE: Although low infliximab trough concentrations and antibodies to infliximab (ATI) are associated with poor outcomes in patients with Crohn's disease (CD), the clinical relevance of ATI in patients with adequate infliximab concentrations is uncertain. We evaluated this question using a...

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Foilsithe in:Gut
Main Authors: Vande Casteele, Niels, Khanna, Reena, Levesque, Barrett G, Stitt, Larry, Zou, G Y, Singh, Sharat, Lockton, Steve, Hauenstein, Scott, Ohrmund, Linda, Greenberg, Gordon R, Rutgeerts, Paul J, Gils, Ann, Sandborn, William J, Vermeire, Séverine, Feagan, Brian G
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMJ Publishing Group 2015
Ábhair:
Inflammatory Bowel Disease
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602247/
https://ncbi.nlm.nih.gov/pubmed/25336114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307883
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