The relationship between infliximab concentrations, antibodies to infliximab and disease activity in Crohn's disease

OBJECTIVE: Although low infliximab trough concentrations and antibodies to infliximab (ATI) are associated with poor outcomes in patients with Crohn's disease (CD), the clinical relevance of ATI in patients with adequate infliximab concentrations is uncertain. We evaluated this question using a...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Vande Casteele, Niels, Khanna, Reena, Levesque, Barrett G, Stitt, Larry, Zou, G Y, Singh, Sharat, Lockton, Steve, Hauenstein, Scott, Ohrmund, Linda, Greenberg, Gordon R, Rutgeerts, Paul J, Gils, Ann, Sandborn, William J, Vermeire, Séverine, Feagan, Brian G
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Inflammatory Bowel Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602247/
https://ncbi.nlm.nih.gov/pubmed/25336114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307883
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