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Evaluation of potential models for imprinted and nonimprinted components of human chromosome 15q11-q13 syndromes by fine-structure homology mapping in the mouse.

Prader-Willi and Angelman syndromes are complex neurobehavioral contiguous gene syndromes whose expression depends on the unmasking of genomic imprinting for different genetic loci in human chromosome 15q11-q13. The homologous chromosomal region in the mouse genome has been fine-mapped by using inte...

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Библиографические подробности
Главные авторы: Nicholls, R D, Gottlieb, W, Russell, L B, Davda, M, Horsthemke, B, Rinchik, E M
Формат: Artigo
Язык:Inglês
Опубликовано: 1993
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC46018/
https://ncbi.nlm.nih.gov/pubmed/8095339
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