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Investigating Apoptozole as a Chemical Probe for HSP70 Inhibition

The use of chemical tools to validate clinical targets has gained in popularity over recent years and the importance of understanding the activity, selectivity and mechanism of action of these compounds is well recognized. Dysregulation of the HSP70 protein family has been linked to multiple cancer...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Evans, Lindsay E., Cheeseman, Matthew D., Yahya, Norhakim, Jones, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601772/
https://ncbi.nlm.nih.gov/pubmed/26458144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140006
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