Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function

Genome-wide association studies have identified multiple risk variants and loci that show robust association with schizophrenia. Nevertheless, it remains unclear how these variants confer risk to schizophrenia. In addition, the driving force that maintains the schizophrenia risk variants in human ge...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: Luo, Xiong-Jian, Mattheisen, Manuel, Li, Ming, Huang, Liang, Rietschel, Marcella, Børglum, Anders D., Als, Thomas D., van den Oord, Edwin J., Aberg, Karolina A., Mors, Ole, Mortensen, Preben Bo, Luo, Zhenwu, Degenhardt, Franziska, Cichon, Sven, Schulze, Thomas G., Nöthen, Markus M., Su, Bing, Zhao, Zhongming, Gan, Lin, Yao, Yong-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601704/
https://ncbi.nlm.nih.gov/pubmed/25759474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbv017
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