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α-synuclein assemblies sequester neuronal α3-Na(+)/K(+)-ATPase and impair Na(+) gradient
Extracellular α-synuclein (α-syn) assemblies can be up-taken by neurons; however, their interaction with the plasma membrane and proteins has not been studied specifically. Here we demonstrate that α-syn assemblies form clusters within the plasma membrane of neurons. Using a proteomic-based approach...
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Publicado no: | EMBO J |
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Main Authors: | , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley & Sons, Ltd
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601662/ https://ncbi.nlm.nih.gov/pubmed/26323479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591397 |
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