In vitro amplification of scrapie and chronic wasting disease PrP(res) using baculovirus-expressed recombinant PrP as substrate

Protein misfolding cyclic amplification (PMCA) is an in vitro simulation of prion replication, which relies on the use of normal brain homogenate derived from host species as substrate for the specific amplification of abnormal prion protein, PrP(Sc). Studies showed that recombinant cellular PrP, Pr...

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Sparad:
Bibliografiska uppgifter
I publikationen:Prion
Huvudupphovsmän: Faburay, Bonto, Tark, Dongseob, Kanthasamy, Anumantha G, Richt, Juergen A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2014
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601224/
https://ncbi.nlm.nih.gov/pubmed/25495764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336896.2014.983753
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