Differential Redox Regulation of Ca(2+) Signaling and Viability in Normal and Malignant Prostate Cells

In prostate cancer, reactive oxygen species (ROS) are elevated and Ca(2+) signaling is impaired. Thus, several novel therapeutic strategies have been developed to target altered ROS and Ca(2+) signaling pathways in prostate cancer. Here, we investigate alterations of intracellular Ca(2+) and inhibit...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Holzmann, Christian, Kilch, Tatiana, Kappel, Sven, Dörr, Kathrin, Jung, Volker, Stöckle, Michael, Bogeski, Ivan, Peinelt, Christine
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2015
Schlagworte:
Channels and Transporters
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601090/
https://ncbi.nlm.nih.gov/pubmed/26445441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.08.006
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