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Structural Analysis of the Pin1-CPEB1 interaction and its potential role in CPEB1 degradation

The Cytoplasmic Polyadenylation Element Binding proteins are RNA binding proteins involved in the translational regulation of mRNA. During cell cycle progression, CPEB1 is labeled for degradation by phosphorylation-dependent ubiquitination by the SCF(β−TrCP) ligase. The peptidyl-prolyl isomerase Pin...

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Publicat a:Sci Rep
Autors principals: Schelhorn, Constanze, Martín-Malpartida, Pau, Suñol, David, Macias, Maria J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601027/
https://ncbi.nlm.nih.gov/pubmed/26456073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14990
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