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Structural Analysis of the Pin1-CPEB1 interaction and its potential role in CPEB1 degradation

The Cytoplasmic Polyadenylation Element Binding proteins are RNA binding proteins involved in the translational regulation of mRNA. During cell cycle progression, CPEB1 is labeled for degradation by phosphorylation-dependent ubiquitination by the SCF(β−TrCP) ligase. The peptidyl-prolyl isomerase Pin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Schelhorn, Constanze, Martín-Malpartida, Pau, Suñol, David, Macias, Maria J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601027/
https://ncbi.nlm.nih.gov/pubmed/26456073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14990
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