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Structural determinants of SMAD function in TGF-β signaling

Smad transcription factors are central to the signal transduction pathway that mediates the numerous effects of the TGF-β superfamily of cytokines in metazoan embryo development and adult tissue regeneration and homeostasis. Although Smad proteins are conserved, recent genome-sequencing projects hav...

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Publicat a:Trends Biochem Sci
Autors principals: Macias, Maria J., Martin-Malpartida, Pau, Massagué, Joan
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485443/
https://ncbi.nlm.nih.gov/pubmed/25935112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2015.03.012
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