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The adipokine leptin mediates muscle- and liver-derived IGF-1 in aged mice
Muscle- and liver-derived IGF-1 play important roles in muscle anabolism throughout growth and aging. Yet, prolonged food restriction is thought to increase longevity in part by lowering levels of IGF-1, which in turn reduces the risk for developing various cancers. The dietary factors that modulate...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Exp Gerontol |
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Κύριοι συγγραφείς: | , , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
2015
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4600673/ https://ncbi.nlm.nih.gov/pubmed/26220769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2015.07.014 |
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