Bypassing P-Glycoprotein Drug Efflux Mechanisms: Possible Applications in Pharmacoresistant Schizophrenia Therapy

The efficient noninvasive treatment of neurodegenerative disorders is often constrained by reduced permeation of therapeutic agents into the central nervous system (CNS). A vast majority of bioactive agents do not readily permeate into the brain tissue due to the existence of the blood-brain barrier...

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Publicat a:Biomed Res Int
Autors principals: Hoosain, Famida G., Choonara, Yahya E., Tomar, Lomas K., Kumar, Pradeep, Tyagi, Charu, du Toit, Lisa C., Pillay, Viness
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
Matèries:
Review Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600488/
https://ncbi.nlm.nih.gov/pubmed/26491671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/484963
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