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Bypassing P-Glycoprotein Drug Efflux Mechanisms: Possible Applications in Pharmacoresistant Schizophrenia Therapy

The efficient noninvasive treatment of neurodegenerative disorders is often constrained by reduced permeation of therapeutic agents into the central nervous system (CNS). A vast majority of bioactive agents do not readily permeate into the brain tissue due to the existence of the blood-brain barrier...

詳細記述

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書誌詳細
出版年:Biomed Res Int
主要な著者: Hoosain, Famida G., Choonara, Yahya E., Tomar, Lomas K., Kumar, Pradeep, Tyagi, Charu, du Toit, Lisa C., Pillay, Viness
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600488/
https://ncbi.nlm.nih.gov/pubmed/26491671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/484963
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