An Epichlorohydrin-Crosslinked Semi-Interpenetrating GG-PEO Network as a Xerogel Matrix for Sustained Release of Sulpiride

The current study involved the development of a novel sustained release crosslinked semi-IPN xerogel matrix tablet prepared by chemical crosslinking of poly(ethylene) oxide (PEO) and gellan gum (GG) employing epichlorohydrin (EPI) as crosslinker. A Box–Behnken design was employed for the statistical...

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Autori principali: Hoosain, Famida G., Choonara, Yahya E., Kumar, Pradeep, Tomar, Lomas K., Tyagi, Charu, du Toit, Lisa C., Pillay, Viness
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179658/
https://ncbi.nlm.nih.gov/pubmed/24920521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0153-4
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