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Human structural variation: mechanisms of chromosome rearrangements
Chromosome structural variation (SV) is a normal part of variation in the human genome, but some classes of SV can cause neurodevelopmental disorders. Analysis of the DNA sequence at SV breakpoints can reveal mutational mechanisms and risk factors for chromosome rearrangement. Large-scale SV breakpo...
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| Publicado no: | Trends Genet |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4600437/ https://ncbi.nlm.nih.gov/pubmed/26209074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2015.05.010 |
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