Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population‐based cohort

Alcohol dependence is frequently co‐morbid with cognitive impairment. The relationship between these traits is complex as cognitive dysfunction may arise as a consequence of heavy drinking or exist prior to the onset of dependence. In the present study, we tested the genetic overlap between cognitiv...

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Pubblicato in:Addict Biol
Autori principali: Clarke, Toni‐Kim, Smith, Andrew H., Gelernter, Joel, Kranzler, Henry R., Farrer, Lindsay A., Hall, Lynsey S., Fernandez‐Pujals, Ana M., MacIntyre, Donald J., Smith, Blair H., Hocking, Lynne J., Padmanabhan, Sandosh, Hayward, Caroline, Thomson, Pippa A., Porteous, David J., Deary, Ian J., McIntosh, Andrew M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
Soggetti:
Human Genetic Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600406/
https://ncbi.nlm.nih.gov/pubmed/25865819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12245
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