Therapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1

Intracellular tumor antigens presented on the cell surface in the context of human leukocyte antigen (HLA) molecules have been targeted by T cell–based therapies, but there has been little progress in developing small-molecule drugs or antibodies directed to these antigens. Here we describe a bispec...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Dao, Tao, Pankov, Dmitry, Scott, Andrew, Korontsvit, Tatyana, Zakhaleva, Victoriya, Xu, Yiyang, Xiang, Jingyi, Yan, Su, de Morais Guerreiro, Manuel Direito, Veomett, Nicholas, Dubrovsky, Leonid, Curcio, Michael, Doubrovina, Ekaterina, Ponomarev, Vladimir, Liu, Cheng, O’Reilly, Richard J, Scheinberg, David A
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600043/
https://ncbi.nlm.nih.gov/pubmed/26389576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3349
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