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Nuclear Localization Signal and p53 Binding Site in MAP/ERK Kinase Kinase 1 (MEKK1)
Previously, we showed that Mekk1 translocates to the nucleus, interacts with tumor suppressor protein p53 and co-represses PKD1 transcription via an atypical p53 binding site on the minimal PKD1 promoter (JBC 285:38818-38831, 2010). In this study, we report the mechanisms of Mekk1 nuclear transport...
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| Publicado en: | J Cell Biochem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4600025/ https://ncbi.nlm.nih.gov/pubmed/26018553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25238 |
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