Impaired hepcidin expression in alpha-1-antitrypsin deficiency associated with iron overload and progressive liver disease

Liver disease due to alpha-1-antitrypsin deficiency (A1ATD) is associated with hepatic iron overload in a subgroup of patients. The underlying cause for this association is unknown. The aim of the present study was to define the genetics of this correlation and the effect of alpha-1-antitrypsin (A1A...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Schaefer, Benedikt, Haschka, David, Finkenstedt, Armin, Petersen, Britt-Sabina, Theurl, Igor, Henninger, Benjamin, Janecke, Andreas R., Wang, Chia-Yu, Lin, Herbert Y., Veits, Lothar, Vogel, Wolfgang, Weiss, Günter, Franke, Andre, Zoller, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599680/
https://ncbi.nlm.nih.gov/pubmed/26310624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv348
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