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ADAMTS13 and von Willebrand Factor in Thrombotic Thrombocytopenic Purpura

Pathogenesis of thrombotic thrombocytopenic purpura (TTP) was a mystery for over half a century until the discovery of ADAMTS13. ADAMTS13 is primarily synthesized in the liver, and its main function is to cleave von Willebrand factor (VWF) anchored on the endothelial surface, in circulation, and at...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Annu Rev Med
Egile nagusia: Zheng, X. Long
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599565/
https://ncbi.nlm.nih.gov/pubmed/25587650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-061813-013241
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