Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome

BACKGROUND: Human genetically inherited cardiac diseases have been studied mainly in heterologous systems or animal models, independent of patients’ genetic backgrounds. Because sources of human cardiomyocytes (CMs) are extremely limited, the use of urine samples to generate induced pluripotent stem...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Jouni, Mariam, Si-Tayeb, Karim, Es-Salah-Lamoureux, Zeineb, Latypova, Xenia, Champon, Benoite, Caillaud, Amandine, Rungoat, Anais, Charpentier, Flavien, Loussouarn, Gildas, Baró, Isabelle, Zibara, Kazem, Lemarchand, Patricia, Gaborit, Nathalie
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599503/
https://ncbi.nlm.nih.gov/pubmed/26330336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002159
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